The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

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phenol

Compound Overview

Name phenol
IUPAC Name phenol
Formula C6H6O
SMILES C1=CC=C(C=C1)O
Carbon Number 6
Molecular Weight 94.11
Polymer Type monomer
Synonyms Benzenol
Carbolic acid
Phenylic acid
Hydroxybenzene
Phenic acid
phenol

Chemical Structure

Chemical structure of phenol

Structure from PubChem

External Databases

CAS 108-95-2
PubChem 996
KEGG C00146
ChEBI 15882
Empirical Data

Organisms that can utilize this substrate (46) Empirical

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Organism ▲ ▼ Strain ▲ ▼ Reference ▲ ▼ Comment ▲ ▼
Rhodococcus rhodochrous 116 Karlson et al (1993) -
Cupriavidus pinatubonensis 1245 Sato et al (2006) -
Cupriavidus laharis 1263a Sato et al (2006) -
Rhodococcus erythropolis 1CP Eulberg et al (1997) -
Amycolatopsis sp. 75iv2 (ATCC 39116) Antai et al (1983), Barton et al (2018) -
Microbotryomycetidae sp. AG15 Bergauer et al (2005) -
Azotobacter vinelandii ATCC 12837 Groseclose et al (1981) -
Cupriavidus necator ATCC 17697 Hughes et al (1983) -
Trichosporon oleaginosus ATCC 20509 Yaguchi et al (2017) -
Phanerochaete chrysosporium ATCC 34541 Nakamura et al (2011) -
Comamonas testosteroni BR6020 Providenti et al (2001) -
Natrialba sp. C21 Khemili-Talbi et al (2015) -
Exophiala jeanselmei CBS 658.76 Middelhoven (1993) -
Trichosporon cutaneum CBS2466 Middelhoven (1993) -
Candida albicans CBS562 Gérecová et al (2015) -
Candida dubliniensis CBS7987 Gérecová et al (2015) -
Candida tropicalis CBS94 Gérecová et al (2015) -
Comamonas testosteroni CNB-1 Ni et al (2012) -
Thauera sp. Cin3,4 Mechichi et al (2005) -
Aromatoleum aromaticum EbN1 Wöhlbrand et al (2007) (anaerobically)
Candida maltosa Fialova isolate Fialová et al (2004) -
Leucosporidium scottii G43 Middelhoven (1993) -
Candida tropicalis HP15 Krug et al (1985) -
Thauera aromatica K172 Tschech et al (1987) (anaerobically)
Burkholderia cepacia KK01 Kato et al (1998) -
Marinobacterium georgiense KW-40 GONZaLEZ et al (1997) -
Pandoraea norimbergensis LD001 Bandounas et al (2011) -
Azoarcus anaerobius LuFRes1 Gorny et al (1992), Gorny et al (1992) (anaerobically)
(anaerobically)
Acetobacterium woodii NZva16 Bache et al (1981) (anaerobically)
Rhodosporidium lusitaniae PB14 Bergauer et al (2005) -
Cryptococcus terreus PB4 Bergauer et al (2005) -
Rhodotorula ingeniosa PB5 Bergauer et al (2005) -
Rhodotorula creatinivora PB7 Bergauer et al (2005) -
Mastigobasidium intermedium PB8 Bergauer et al (2005) -
Rhodococcus opacus PD630 (DSMZ 44193) Henson et al (2018) -
Pseudomonas fluorescens PU1 Mahiudddin et al (2012) -
Desulfobacterium phenolicum Ph01 Bak et al (1986) (anaerobically)
Rhodococcus jostii RHA1 Otani et al (2014) -
Acinetobacter radioresistens S13 Mazzoli et al (2007) -
Trichosporon mucoides SBUG 80 Sietmann et al (2001) -
Petriellidium boydii SP 31-4 Eriksson et al (1984) -
Trametes versicolor Strain 1 Alexieva et al (2010) -
Novosphingobium taihuense T3-B9 Liu et al (2005) -
Rhodococcus erythropolis TA421 Chung et al (1994) -
Rhodococcus sp. UKMP-5M Suhaila et al (2013) -
Acinetobacter tandoii Van Dexter isolate Van Dexter et al (2018) -

Pathways Empirical

Pathway Name Full Name
phenol phenol
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted to process phenol through a pathway Predicted

For each pathway where phenol enters as a reactant, organisms recorded as being able to utilise it but not yet confirmed for that pathway are listed as predicted. Not experimentally verified. What does this mean?

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Organism Strain Inferred via pathway Reference confirming phenol utilization
Acetobacterium woodii NZva16 phenol Bache et al (1981)
Acinetobacter radioresistens S13 phenol Mazzoli et al (2007)
Acinetobacter tandoii Van Dexter isolate phenol Van Dexter et al (2018)
Amycolatopsis sp. 75iv2 (ATCC 39116) phenol Antai et al (1983), Barton et al (2018)
Aromatoleum aromaticum EbN1 phenol Wöhlbrand et al (2007)
Azoarcus anaerobius LuFRes1 phenol Gorny et al (1992)
Azotobacter vinelandii ATCC 12837 phenol Groseclose et al (1981)
Burkholderia cepacia KK01 phenol Kato et al (1998)
Candida albicans CBS562 phenol Gérecová et al (2015)
Candida dubliniensis CBS7987 phenol Gérecová et al (2015)
Candida maltosa Fialova isolate phenol Fialová et al (2004)
Candida tropicalis CBS94 phenol Gérecová et al (2015)
Candida tropicalis HP15 phenol Krug et al (1985)
Comamonas testosteroni BR6020 phenol Providenti et al (2001)
Comamonas testosteroni CNB-1 phenol Ni et al (2012)
Cryptococcus terreus PB4 phenol Bergauer et al (2005)
Cupriavidus laharis 1263a phenol Sato et al (2006)
Cupriavidus necator ATCC 17697 phenol Hughes et al (1983)
Cupriavidus pinatubonensis 1245 phenol Sato et al (2006)
Desulfobacterium phenolicum Ph01 phenol Bak et al (1986)
Exophiala jeanselmei CBS 658.76 phenol Middelhoven (1993)
Leucosporidium scottii G43 phenol Middelhoven (1993)
Marinobacterium georgiense KW-40 phenol GONZaLEZ et al (1997)
Mastigobasidium intermedium PB8 phenol Bergauer et al (2005)
Microbotryomycetidae sp. AG15 phenol Bergauer et al (2005)
Natrialba sp. C21 phenol Khemili-Talbi et al (2015)
Novosphingobium taihuense T3-B9 phenol Liu et al (2005)
Pandoraea norimbergensis LD001 phenol Bandounas et al (2011)
Petriellidium boydii SP 31-4 phenol Eriksson et al (1984)
Phanerochaete chrysosporium ATCC 34541 phenol Nakamura et al (2011)
Pseudomonas fluorescens PU1 phenol Mahiudddin et al (2012)
Rhodococcus erythropolis 1CP phenol Eulberg et al (1997)
Rhodococcus erythropolis TA421 phenol Chung et al (1994)
Rhodococcus jostii RHA1 phenol Otani et al (2014)
Rhodococcus rhodochrous 116 phenol Karlson et al (1993)
Rhodococcus sp. UKMP-5M phenol Suhaila et al (2013)
Rhodosporidium lusitaniae PB14 phenol Bergauer et al (2005)
Rhodotorula creatinivora PB7 phenol Bergauer et al (2005)
Rhodotorula ingeniosa PB5 phenol Bergauer et al (2005)
Thauera aromatica K172 phenol Tschech et al (1987)
Thauera sp. Cin3,4 phenol Mechichi et al (2005)
Trametes versicolor Strain 1 phenol Alexieva et al (2010)
Trichosporon cutaneum CBS2466 phenol Middelhoven (1993)
Trichosporon mucoides SBUG 80 phenol Sietmann et al (2001)
Trichosporon oleaginosus ATCC 20509 phenol Yaguchi et al (2017)

Reactions involving phenol

Reaction Role in Reaction
phenol + NADPH + O2 + H+ → catechol + NADP+ + H2O substrate

Transporters

No transporters are currently linked to this substrate.

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