The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

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p-coumaric acid

Compound Overview

Name p-coumaric acid
IUPAC Name (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid
Formula C9H8O3
SMILES C1=CC(=CC=C1C=CC(=O)O)O
Carbon Number 9
Molecular Weight 164.16
Polymer Type monomer
Synonyms trans-p-coumaric acid
trans-p-coumarinic acid
trans-p-Hydroxycinnamate
trans-p-hydroxycinnamic acid
naringeninic acid
4-Hydroxycinnamic acid
(E)-p-coumaric acid
(E)-p-hydroxycinnamic acid
p-coumarate
(2E)-3-(4-hydroxyphenyl)prop-2-enoic acid

Chemical Structure

Chemical structure of p-coumaric acid

Structure from PubChem

External Databases

CAS 501-98-4
PubChem 637542
KEGG C00811
ChEBI 32374
Empirical Data

Organisms that can utilize this substrate (22) Empirical

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Organism ▲ ▼ Strain ▲ ▼ Reference ▲ ▼ Comment ▲ ▼
Fusarium oxysporum 4287 Michielse et al (2012) -
Amycolatopsis sp. 75iv2 (ATCC 39116) Davis et al (2012), Sutherland et al (1983), Barton et al (2018) -
Acinetobacter baylyi ADP1 Salvachúa et al (2015), Fischer et al (2008) -
Paraburkholderia aromaticivorans AR20-38 Margesin et al (2021) -
Comamonas sp. B-9 (CGMCC No. 4251) Chen et al (2012) -
Exophiala jeanselmei CBS 658.76 Middelhoven (1993) -
Rhodotorula mucilaginosa CBS17 Sampaio (1999) -
Rhodopseudomonas palustris CGA001 Harwood et al (1988) Reported as: 4-hydroxycinnamic acid
Rhodopseudomonas palustris CGA009 Salmon et al (2013) -
Thauera sp. Cin3,4 Mechichi et al (2005) (anaerobically)
Rhodosporidiobolus colostri DBVPG 10655 Margesin et al (2022) -
Acinetobacter calcoaceticus DSM 586 Delneri et al (1995) -
Rhodosporidium toruloides IFO0880 Yaegashi et al (2017) -
Pseudomonas sp. Isolate 9.1 Ravi et al (2018) -
Oceanimonas doudoroffii JCM21046T Numata et al (2015) -
Cupriavidus necator JMP134 Pérez-Pantoja et al (2008) -
Burkholderia cepacia KK01 Kato et al (1998) -
Pseudomonas putida KT2440 Salvachúa et al (2015), Ravi et al (2017) -
Marinobacterium georgiense KW-40 GONZaLEZ et al (1997) -
Brettanomyces anomalus NCYC 615 Edlin et al (1995) -
Pseudomonas putida Perestelo isolate 3 Perestelo et al (1996) -
Rhodococcus jostii RHA1 Salvachúa et al (2015) -

Pathways Empirical

Pathway Name Full Name
p-coumaric acid p-coumaric acid
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted to process p-coumaric acid through a pathway Predicted

For each pathway where p-coumaric acid enters as a reactant, organisms recorded as being able to utilise it but not yet confirmed for that pathway are listed as predicted. Not experimentally verified. What does this mean?

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Organism Strain Inferred via pathway Reference confirming p-coumaric acid utilization
Acinetobacter baylyi ADP1 p-coumaric acid Salvachúa et al (2015), Fischer et al (2008)
Acinetobacter calcoaceticus DSM 586 p-coumaric acid Delneri et al (1995)
Brettanomyces anomalus NCYC 615 p-coumaric acid Edlin et al (1995)
Burkholderia cepacia KK01 p-coumaric acid Kato et al (1998)
Comamonas sp. B-9 (CGMCC No. 4251) p-coumaric acid Chen et al (2012)
Cupriavidus necator JMP134 p-coumaric acid Pérez-Pantoja et al (2008)
Exophiala jeanselmei CBS 658.76 p-coumaric acid Middelhoven (1993)
Fusarium oxysporum 4287 p-coumaric acid Michielse et al (2012)
Marinobacterium georgiense KW-40 p-coumaric acid GONZaLEZ et al (1997)
Oceanimonas doudoroffii JCM21046T p-coumaric acid Numata et al (2015)
Paraburkholderia aromaticivorans AR20-38 p-coumaric acid Margesin et al (2021)
Pseudomonas putida Perestelo isolate 3 p-coumaric acid Perestelo et al (1996)
Pseudomonas sp. Isolate 9.1 p-coumaric acid Ravi et al (2018)
Rhodococcus jostii RHA1 p-coumaric acid Salvachúa et al (2015)
Rhodopseudomonas palustris CGA001 p-coumaric acid Harwood et al (1988)
Rhodopseudomonas palustris CGA009 p-coumaric acid Salmon et al (2013)
Rhodosporidiobolus colostri DBVPG 10655 p-coumaric acid Margesin et al (2022)
Rhodosporidium toruloides IFO0880 p-coumaric acid Yaegashi et al (2017)
Rhodotorula mucilaginosa CBS17 p-coumaric acid Sampaio (1999)
Thauera sp. Cin3,4 p-coumaric acid Mechichi et al (2005)

Reactions involving p-coumaric acid

Reaction Role in Reaction
p-coumaric acid + CoA + ATP → p-coumaroyl-CoA + AMP + PPi substrate

Transporters

No transporters are currently linked to this substrate.

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