Funneling pathway: p-cresol
- Full Name
- p-cresol
- Funneling Branch
- p-coumaric branch
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Interactive metabolic pathway map showing compounds (text labels) connected by reaction arrows. Click arrows to view reaction details, click compounds to view substrate details. Zoom with mouse wheel, pan by dragging.
Organisms with this Pathway Empirical
| Organism | Strain | Reference(s) |
|---|---|---|
| Pseudomonas putida | NCIMB 9866 | Cronin et al (1999) |
Organisms predicted for this pathway Predicted
Inferred from reported substrate utilization: organisms that can utilise a compound entering this pathway as a reactant are predicted to carry the pathway, unless already confirmed. The reference confirming substrate use is shown. Not experimentally verified. What does this mean?
| Predicted organism | Strain | Inferred via substrate | Reference |
|---|---|---|---|
| Aromatoleum aromaticum | EbN1 | 4-cresol | Wöhlbrand et al (2007) |
| Azoarcus anaerobius | LuFRes1 | 4-cresol | Gorny et al (1992) |
| Azotobacter vinelandii | ATCC 12837 | 4-cresol | Groseclose et al (1981) |
| Burkholderia cepacia | KK01 | 4-cresol | Kato et al (1998) |
| Corynebacterium glutamicum | ATCC13032 | 4-cresol | Qi et al (2007) |
| Cupriavidus necator | ATCC 17697 | 4-cresol | Hughes et al (1983) |
| Desulfobacterium phenolicum | Ph01 | 4-cresol | Bak et al (1986) |
| Exophiala jeanselmei | CBS 658.76 | 4-cresol | Middelhoven (1993) |
| Micrococcus luteus | E1.1 | 4-cresol | Taylor et al (2012) |
| Rhodococcus erythropolis | A5.1 | 4-cresol | Taylor et al (2012) |
| Rhodococcus jostii | RHA1 | 4-cresol | Otani et al (2014) |
| Rhodotorula creatinivora | PB7 | 4-cresol | Bergauer et al (2005) |
| Sphingomonas aromaticivorans | F199 | 4-cresol | BALKWILL et al (1997) |
| Thauera aromatica | K172 | 4-cresol | Tschech et al (1987) |
| Thauera sp. | Cin3,4 | 4-cresol | Mechichi et al (2005) |
| Trametes versicolor | Strain 1 | 4-cresol | Alexieva et al (2010) |
Predicted enzyme assignments for confirmed organisms Predicted
Inferred from confirmed pathway membership: if an organism is confirmed to carry this pathway, enzymes known to catalyse reactions within it are predicted to be present. The reference confirming the organism’s membership of this pathway is shown. Not experimentally verified. What does this mean?
No predicted enzyme assignments: all confirmed organisms are already linked to the enzymes of this pathway.
Reactions in this Pathway
| Order | Substrates | Products | Enzyme(s) | Reaction | |
|---|---|---|---|---|---|
| 1 | p-cresol | → | 4-hydroxybenzyl alcohol | 4-methylphenol methylhydroxylase | R00071 |
| 2 | 4-hydroxybenzyl alcohol | → | 4-hydroxybenzaldehyde | 4-methylphenol methylhydroxylase | R00072 |
Compounds (Substrates & Products)
Intermediate metabolites that are not registered in the Substrate table are shown as plain text without a hyperlink.
| Compound Name | Formula | SMILES | PubChem | Role |
|---|---|---|---|---|
| p-cresol | CH3C6H4OH |
CC1=CC=C(C=C1)O
|
2879 | substrate |
| 4-hydroxybenzyl alcohol (intermediate) | C7H8O2 |
C1=CC(=CC=C1CO)O
|
125 | product, substrate |
| 4-hydroxybenzaldehyde | C7H6O2 |
C1=CC(=CC=C1C=O)O
|
126 | product |
Connected Pathways
Outgoing Connections (This pathway connects to:)
Genes
Other Databases
| Database | Comment |
|---|---|
| MetaCyc | Metabolic pathway database |