The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

brinkdp/eLignin 0 0

Funneling pathway: resorcinol

Full Name
resorcinol
Funneling Branch
resorcinol branch

Pathway Network Visualization 📥 Export BioPAX JSON-LD

Interactive metabolic pathway map showing compounds (text labels) connected by reaction arrows. Click arrows to view reaction details, click compounds to view substrate details. Zoom with mouse wheel, pan by dragging.

Empirical Data

Organisms with this Pathway Empirical

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Organism Strain Reference(s)
Corynebacterium glutamicum ATCC13032 Huang et al (2006)
Rhodococcus jostii RHA1 Kasai et al (2015)
Pseudomonas putida ORC Chapman et al (1976)
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted for this pathway Predicted

Inferred from reported substrate utilization: organisms that can utilise a compound entering this pathway as a reactant are predicted to carry the pathway, unless already confirmed. The reference confirming substrate use is shown. Not experimentally verified. What does this mean?

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Predicted organism Strain Inferred via substrate Reference
Azoarcus anaerobius LuFRes1 resorcinol Gorny et al (1992)
Azotobacter vinelandii ATCC 12837 resorcinol Groseclose et al (1981)
Burkholderia cepacia Song isolate 1 resorcinol Song (2009)
Burkholderia sp. H1 resorcinol Yang et al (2017)
Candida albicans CBS562 resorcinol Gérecová et al (2015)
Candida dubliniensis CBS7987 resorcinol Gérecová et al (2015)
Candida maltosa Fialova isolate resorcinol Fialová et al (2004)
Candida orthopsilosis MCO457 resorcinol Gérecová et al (2015)
Candida parapsilosis CBS604 resorcinol Middelhoven (1993), Gérecová et al (2015)
Candida tropicalis CBS94 resorcinol Gérecová et al (2015)
Candida tropicalis HP15 hydroxyquinol, resorcinol Krug et al (1985)
Cryptococcus terreus PB4 resorcinol Bergauer et al (2005)
Desulfobacterium catecholicum NZva20 resorcinol Szewzyk et al (1987)
Exophiala jeanselmei CBS 658.76 resorcinol Middelhoven (1993)
Leucosporidium scottii G43 resorcinol Middelhoven (1993)
Mastigobasidium intermedium PB8 resorcinol Bergauer et al (2005)
Microbotryomycetidae sp. AG15 resorcinol Bergauer et al (2005)
Rhodosporidium lusitaniae PB14 resorcinol Bergauer et al (2005)
Rhodotorula creatinivora PB7 resorcinol Bergauer et al (2005)
Rhodotorula ingeniosa PB5 resorcinol Bergauer et al (2005)
Thauera aromatica K172 resorcinol Tschech et al (1987)
Trichosporon oleaginosus ATCC 20509 resorcinol Yaguchi et al (2017)

Predicted enzyme assignments for confirmed organisms Predicted

Inferred from confirmed pathway membership: if an organism is confirmed to carry this pathway, enzymes known to catalyse reactions within it are predicted to be present. The reference confirming the organism’s membership of this pathway is shown. Not experimentally verified. What does this mean?

Organism Strain Predicted enzyme Reference confirming pathway
Rhodococcus jostii RHA1 hydroxyquinol 1,2-dioxygenase I Kasai et al (2015)
Pseudomonas putida ORC hydroxyquinol 1,2-dioxygenase I Chapman et al (1976)
Rhodococcus jostii RHA1 hydroxyquinol 1,2-dioxygenase II Kasai et al (2015)
Pseudomonas putida ORC hydroxyquinol 1,2-dioxygenase II Chapman et al (1976)
Rhodococcus jostii RHA1 maleylacetate reductase I Kasai et al (2015)
Pseudomonas putida ORC maleylacetate reductase I Chapman et al (1976)
Rhodococcus jostii RHA1 maleylacetate reductase II Kasai et al (2015)
Pseudomonas putida ORC maleylacetate reductase II Chapman et al (1976)
Rhodococcus jostii RHA1 resorcinol 4-hydroxylase Kasai et al (2015)
Pseudomonas putida ORC resorcinol 4-hydroxylase Chapman et al (1976)

Reactions in this Pathway

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Order Substrates Products Enzyme(s) Reaction
1 resorcinol → hydroxyquinol resorcinol 4-hydroxylase R00043
2 hydroxyquinol → 2-maleylacetate hydroxyquinol 1,2-dioxygenase I , hydroxyquinol 1,2-dioxygenase II R00044
3 2-maleylacetate → Beta-ketoadipate maleylacetate reductase I , maleylacetate reductase II R00045

Compounds (Substrates & Products)

Intermediate metabolites that are not registered in the Substrate table are shown as plain text without a hyperlink.

Compound Name Formula SMILES PubChem Role
resorcinol C6H6O2 C1=CC(=CC(=C1)O)O 5054 substrate
hydroxyquinol C6H6O3 C1=CC(=C(C=C1O)O)O 10787 product, substrate
2-maleylacetate (intermediate) C6H6O5 C(C(=O)C=CC(=O)O)C(=O)O 5280500 product, substrate
Beta-ketoadipate (intermediate) C6H8O5 C(CC(=O)O)C(=O)CC(=O)O 93 product

Connected Pathways

Outgoing Connections (This pathway connects to:)

Connected Pathway Connecting Compound
Fission pathway: beta-ketoadipate: lower branch -

Genes

Gene Enzyme
Cgl1158 resorcinol 4-hydroxylase
Cgl1160 hydroxyquinol 1,2-dioxygenase I
Cgl3056 hydroxyquinol 1,2-dioxygenase II
Cgl1159 maleylacetate reductase I
Cgl3057 maleylacetate reductase II

Other Databases

Database Comment
MetaCyc Metabolic pathway database

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