The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

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Fission pathway: beta-ketoadipate: lower branch

Full Name
beta-ketoadipate: lower branch
Funneling Branch
beta-ketoadipate branch
Synonyms
3-oxoadipate pathway: lower branch
3-ketoadipate pathway: lower branch

Pathway Network Visualization 📥 Export BioPAX JSON-LD

Interactive metabolic pathway map showing compounds (text labels) connected by reaction arrows. Click arrows to view reaction details, click compounds to view substrate details. Zoom with mouse wheel, pan by dragging.

Empirical Data

Organisms with this Pathway Empirical

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Organism Strain Reference(s)
Pseudomonas putida KT2440 Jiménez et al (2002)
Corynebacterium glutamicum ATCC13032 Shen et al (2012)
Pseudomonas putida PRS2000 Ornston et al (1976)
Pseudomonas putida ORC Chapman et al (1976)
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted for this pathway Predicted

Inferred from reported substrate utilization: organisms that can utilise a compound entering this pathway as a reactant are predicted to carry the pathway, unless already confirmed. The reference confirming substrate use is shown. Not experimentally verified. What does this mean?

No organisms predicted for this pathway based on current substrate data.

Predicted enzyme assignments for confirmed organisms Predicted

Inferred from confirmed pathway membership: if an organism is confirmed to carry this pathway, enzymes known to catalyse reactions within it are predicted to be present. The reference confirming the organism’s membership of this pathway is shown. Not experimentally verified. What does this mean?

No predicted enzyme assignments: all confirmed organisms are already linked to the enzymes of this pathway.

Reactions in this Pathway

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Order Substrates Products Enzyme(s) Reaction
1 beta-ketoadipate-enol-lactone → beta-ketoadipate - R00004
2 beta-ketoadipate → beta-oxoadipyl-CoA - R00005
3 beta-oxoadipyl-CoA → acetyl-CoA + succinyl-CoA - R00006

Compounds (Substrates & Products)

Intermediate metabolites that are not registered in the Substrate table are shown as plain text without a hyperlink.

Compound Name Formula SMILES PubChem Role
beta-ketoadipate-enol-lactone (intermediate) C6H6O4 C1C=C(OC1=O)CC(=O)O 104 substrate
beta-ketoadipate (intermediate) C6H8O5 C(CC(=O)O)C(=O)CC(=O)O 93 product, substrate
beta-oxoadipyl-CoA (intermediate) C27H42N7O20P3S CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CC(=O)CCC(=O)O)O 9543153 product, substrate
acetyl-CoA (intermediate) C23H38N7O17P3S CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O 444493 product
succinyl-CoA (intermediate) C25H40N7O19P3S CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CCC(=O)O)O 92133 product

Connected Pathways

Incoming Connections (Pathways connecting to this one:)

Source Pathway Connecting Compound
Fission pathway: beta-ketoadipate: Catechol branch -
Fission pathway: beta-ketoadipate: Protocatechuate branch -
Funneling pathway: resorcinol -

Genes

No genes defined in this pathway's BioPAX snapshot.

Other Databases

Database Comment
MetaCyc Metabolic pathway database

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