The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

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guaiacol

Compound Overview

Name guaiacol
IUPAC Name 2-methoxyphenol
Formula C7H8O2
SMILES COC1=CC=CC=C1O
Carbon Number 7
Molecular Weight 124.14
Polymer Type monomer
Synonyms 1-Hydroxy-2-methoxybenzene
2-Hydroxyanisole
2-methoxyphenol
Catechol monomethyl ether
o-Methoxyphenol

Chemical Structure

Chemical structure of guaiacol

Structure from PubChem

External Databases

CAS 90-05-01
PubChem 460
KEGG C01502
ChEBI 28591
Empirical Data

Organisms that can utilize this substrate (19) Empirical

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Organism ▲ ▼ Strain ▲ ▼ Reference ▲ ▼ Comment ▲ ▼
Rhodococcus rhodochrous 116 Karlson et al (1993) -
Acinetobacter junii 5ga González et al (1993) -
Amycolatopsis sp. 75iv2 (ATCC 39116) Davis et al (2012), Pometto III et al (1981), Sutherland et al (1983), Barton et al (2018) -
Comamonas sp. B-9 (CGMCC No. 4251) Chen et al (2012) -
Enterobacter sp. DG-6 Grbić-Galić (1985) (anaerobically)
Rhodococcus opacus DSM 1069 Ravi et al (2018) -
Ceriporiopsis subvermispora FP-105752 Daina et al (2002) -
Moraxella sp. GU2 Dardas et al (1985), Sterjiades et al (1982) -
Rhodotorula rubra IFO 889 Huang et al (1993) -
Serratia sp. JHT01 Tian et al (2016) -
Burkholderia cepacia KK01 Kato et al (1998) -
Desulfobacterium catecholicum NZva20 Szewzyk et al (1987) (anaerobically)
Pseudomonas putida ORC Chapman et al (1976) -
Rhodococcus opacus PD630 (DSMZ 44193) Henson et al (2018) -
Serratia liquefaciens sp. PT01 Tian et al (2016) -
Pseudomonas chlororaphis subsp. aureofaciens PT02 Tian et al (2016) -
Stenotrophomonas sp. PT03 Tian et al (2016) -
Mesorhizobium sp. PT04 Tian et al (2016) -
Paenibacillus glucanolyticus SLM1 Mathews et al (2014) -

Pathways Empirical

Pathway Name Full Name
guaiacol guaiacol
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted to process guaiacol through a pathway Predicted

For each pathway where guaiacol enters as a reactant, organisms recorded as being able to utilise it but not yet confirmed for that pathway are listed as predicted. Not experimentally verified. What does this mean?

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Organism Strain Inferred via pathway Reference confirming guaiacol utilization
Acinetobacter junii 5ga guaiacol González et al (1993)
Burkholderia cepacia KK01 guaiacol Kato et al (1998)
Ceriporiopsis subvermispora FP-105752 guaiacol Daina et al (2002)
Comamonas sp. B-9 (CGMCC No. 4251) guaiacol Chen et al (2012)
Desulfobacterium catecholicum NZva20 guaiacol Szewzyk et al (1987)
Enterobacter sp. DG-6 guaiacol Grbić-Galić (1985)
Mesorhizobium sp. PT04 guaiacol Tian et al (2016)
Moraxella sp. GU2 guaiacol Dardas et al (1985), Sterjiades et al (1982)
Paenibacillus glucanolyticus SLM1 guaiacol Mathews et al (2014)
Pseudomonas chlororaphis subsp. aureofaciens PT02 guaiacol Tian et al (2016)
Pseudomonas putida ORC guaiacol Chapman et al (1976)
Rhodococcus opacus DSM 1069 guaiacol Ravi et al (2018)
Rhodococcus rhodochrous 116 guaiacol Karlson et al (1993)
Serratia liquefaciens sp. PT01 guaiacol Tian et al (2016)
Serratia sp. JHT01 guaiacol Tian et al (2016)
Stenotrophomonas sp. PT03 guaiacol Tian et al (2016)

Reactions involving guaiacol

Reaction Role in Reaction
Guaiacol + O2 + H+ → Catechol + Formaldehyde + H2O Substrate
vanillic acid → guaiacol + CO2 product

Transporters

No transporters are currently linked to this substrate.

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