The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

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gentisic acid

Compound Overview

Name gentisic acid
IUPAC Name 2,5-dihydroxybenzoic acid
Formula C7H6O4
SMILES C1=CC(=C(C=C1O)C(=O)O)O
Carbon Number 7
Molecular Weight 154.12
Polymer Type monomer
Synonyms Gentisate
2,5-Dihydroxybenzoate
5-hydroxysalicylic acid
Hydroquinonecarboxylic acid
2,5-dihydroxybenzoic acid

Chemical Structure

Chemical structure of gentisic acid

Structure from PubChem

External Databases

CAS 490-79-9
PubChem 3469
KEGG C00628
ChEBI 17189
Empirical Data

Organisms that can utilize this substrate (10) Empirical

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Organism Strain Reference Comment
Amycolatopsis sp. 75iv2 (ATCC 39116) Davis et al (2012), Pometto III et al (1981) -
Corynebacterium glutamicum ATCC13032 Qi et al (2007) -
Exophiala jeanselmei CBS 658.76 Middelhoven (1993) -
Candida parapsilosis CBS604 Middelhoven (1993), Gérecová et al (2015) -
Comamonas testosteroni CNB-1 Ni et al (2012) -
Haloarcula sp. D1 Fairley et al (2002) -
Oceanimonas doudoroffii JCM21046T Numata et al (2015) -
Burkholderia cepacia Song isolate 1 Song (2009) -
Flavimonas oryzihabitans Song isolate 4 Song (2009) -
Streptomyces viridosporus T7A Zeng et al (2012) -

Pathways Empirical

Pathway Name Full Name
gentisate-cleavage gentisate-cleavage
salicylic acid II salicylic acid II
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted to process gentisic acid through a pathway Predicted

For each pathway where gentisic acid enters as a reactant, organisms recorded as being able to utilise it but not yet confirmed for that pathway are listed as predicted. Not experimentally verified. What does this mean?

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Organism Strain Inferred via pathway Reference confirming gentisic acid utilization
Amycolatopsis sp. 75iv2 (ATCC 39116) gentisate-cleavage Davis et al (2012), Pometto III et al (1981)
Burkholderia cepacia Song isolate 1 gentisate-cleavage Song (2009)
Comamonas testosteroni CNB-1 gentisate-cleavage Ni et al (2012)
Exophiala jeanselmei CBS 658.76 gentisate-cleavage Middelhoven (1993)
Flavimonas oryzihabitans Song isolate 4 gentisate-cleavage Song (2009)
Oceanimonas doudoroffii JCM21046T gentisate-cleavage Numata et al (2015)
Streptomyces viridosporus T7A gentisate-cleavage Zeng et al (2012)

Reactions involving gentisic acid

Transporters

Transporter Reference
Cg_nagTp Xu et al (2006)

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