The eLignin Microbial Database

A curated resource for microbial metabolism of lignin-derived aromatic compounds

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syringic acid

Compound Overview

Name syringic acid
IUPAC Name 4-hydroxy-3,5-dimethoxybenzoic acid
Formula C9H10O5
SMILES COC1=CC(=CC(=C1O)OC)C(=O)O
Carbon Number 9
Molecular Weight 198.17
Polymer Type monomer
Synonyms Cedar acid
Gallic acid 3,5-dimethyl ether
4-hydroxy-3,5-dimethoxybenzoic acid
Syringate

Chemical Structure

Chemical structure of syringic acid

Structure from PubChem

External Databases

CAS 530-57-4
PubChem 10742
KEGG C10833
ChEBI 68329
Empirical Data

Organisms that can utilize this substrate (17) Empirical

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Organism ▲ ▼ Strain ▲ ▼ Reference ▲ ▼ Comment ▲ ▼
Phialophora mutabilis 203-E-15-y-l Eriksson et al (1984) -
Clostridium thermoaceticum ATCC 39073 Daniel et al (1988) (anaerobically)
Exophiala jeanselmei CBS 658.76 Middelhoven (1993) -
Enterobacter sp. DG-6 Grbić-Galić (1985) (anaerobically)
Oceanimonas doudoroffii JCM21046T Numata et al (2015) -
Serratia sp. JHT01 Tian et al (2016) -
Pandoraea norimbergensis LD001 Bandounas et al (2011) -
Acetobacterium dehalogenans MC Kaufmann et al (1998) (anaerobically)
Acetobacterium woodii NZva16 Bache et al (1981) (anaerobically)
Serratia liquefaciens sp. PT01 Tian et al (2016) -
Pseudomonas chlororaphis subsp. aureofaciens PT02 Tian et al (2016) -
Stenotrophomonas sp. PT03 Tian et al (2016) -
Petriellidium boydii SP 31-4 Eriksson et al (1984) -
Clostridium methoxybenzovorans SR3 Mechichi et al (1999), Mechichi et al (2005) (anaerobically)
(anaerobically)
Sphingobium sp. SYK-6 Katayama et al (1988), Masai et al (2004) -
Holophaga foetida TMBS4 Bak et al (1993) (anaerobically)
Rhizobium sp. YS-1r Jackson et al (2017) -

Pathways Empirical

Pathway Name Full Name
syringic acid I syringic acid I
syringic acid II syringic acid II
syringic acid III syringic acid III
sinapic acid sinapic acid
Predicted Relationships Hide predicted
The sections below contain relationships inferred from the empirical data above. They are computationally predicted and have not been independently verified. Learn more about data assumptions →
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Organisms predicted to process syringic acid through a pathway Predicted

For each pathway where syringic acid enters as a reactant, organisms recorded as being able to utilise it but not yet confirmed for that pathway are listed as predicted. Not experimentally verified. What does this mean?

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Organism Strain Inferred via pathway Reference confirming syringic acid utilization
Acetobacterium dehalogenans MC syringic acid I Kaufmann et al (1998)
Acetobacterium woodii NZva16 syringic acid I Bache et al (1981)
Clostridium methoxybenzovorans SR3 syringic acid I Mechichi et al (1999), Mechichi et al (2005)
Clostridium thermoaceticum ATCC 39073 syringic acid I Daniel et al (1988)
Enterobacter sp. DG-6 syringic acid I Grbić-Galić (1985)
Exophiala jeanselmei CBS 658.76 syringic acid I Middelhoven (1993)
Holophaga foetida TMBS4 syringic acid I Bak et al (1993)
Oceanimonas doudoroffii JCM21046T syringic acid I Numata et al (2015)
Pandoraea norimbergensis LD001 syringic acid I Bandounas et al (2011)
Petriellidium boydii SP 31-4 syringic acid I Eriksson et al (1984)
Phialophora mutabilis 203-E-15-y-l syringic acid I Eriksson et al (1984)
Pseudomonas chlororaphis subsp. aureofaciens PT02 syringic acid I Tian et al (2016)
Rhizobium sp. YS-1r syringic acid I Jackson et al (2017)
Serratia liquefaciens sp. PT01 syringic acid I Tian et al (2016)
Serratia sp. JHT01 syringic acid I Tian et al (2016)
Stenotrophomonas sp. PT03 syringic acid I Tian et al (2016)
Acetobacterium dehalogenans MC syringic acid II Kaufmann et al (1998)
Acetobacterium woodii NZva16 syringic acid II Bache et al (1981)
Clostridium methoxybenzovorans SR3 syringic acid II Mechichi et al (1999), Mechichi et al (2005)
Clostridium thermoaceticum ATCC 39073 syringic acid II Daniel et al (1988)
Enterobacter sp. DG-6 syringic acid II Grbić-Galić (1985)
Exophiala jeanselmei CBS 658.76 syringic acid II Middelhoven (1993)
Holophaga foetida TMBS4 syringic acid II Bak et al (1993)
Oceanimonas doudoroffii JCM21046T syringic acid II Numata et al (2015)
Pandoraea norimbergensis LD001 syringic acid II Bandounas et al (2011)
Petriellidium boydii SP 31-4 syringic acid II Eriksson et al (1984)
Phialophora mutabilis 203-E-15-y-l syringic acid II Eriksson et al (1984)
Pseudomonas chlororaphis subsp. aureofaciens PT02 syringic acid II Tian et al (2016)
Rhizobium sp. YS-1r syringic acid II Jackson et al (2017)
Serratia liquefaciens sp. PT01 syringic acid II Tian et al (2016)
Serratia sp. JHT01 syringic acid II Tian et al (2016)
Stenotrophomonas sp. PT03 syringic acid II Tian et al (2016)
Acetobacterium dehalogenans MC syringic acid III Kaufmann et al (1998)
Acetobacterium woodii NZva16 syringic acid III Bache et al (1981)
Clostridium methoxybenzovorans SR3 syringic acid III Mechichi et al (1999), Mechichi et al (2005)
Clostridium thermoaceticum ATCC 39073 syringic acid III Daniel et al (1988)
Enterobacter sp. DG-6 syringic acid III Grbić-Galić (1985)
Exophiala jeanselmei CBS 658.76 syringic acid III Middelhoven (1993)
Holophaga foetida TMBS4 syringic acid III Bak et al (1993)
Oceanimonas doudoroffii JCM21046T syringic acid III Numata et al (2015)
Pandoraea norimbergensis LD001 syringic acid III Bandounas et al (2011)
Petriellidium boydii SP 31-4 syringic acid III Eriksson et al (1984)
Phialophora mutabilis 203-E-15-y-l syringic acid III Eriksson et al (1984)
Pseudomonas chlororaphis subsp. aureofaciens PT02 syringic acid III Tian et al (2016)
Rhizobium sp. YS-1r syringic acid III Jackson et al (2017)
Serratia liquefaciens sp. PT01 syringic acid III Tian et al (2016)
Serratia sp. JHT01 syringic acid III Tian et al (2016)
Stenotrophomonas sp. PT03 syringic acid III Tian et al (2016)

Reactions involving syringic acid

Reaction Role in Reaction
syringic acid + tetrahydrofolate → 3-O-methylgallate + 5-methyltetrahydrofolate substrate
Syringaldehyde + NAD+ + H2O → Syringic acid +NADPH +H+ product

Transporters

No transporters are currently linked to this substrate.

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